Started to happen about a year ago, I will get no sound at all coming from the sound card and windows shows there is no output from it. Rebooting does not fix the issue, only way to fix is to uninstall the drivers and reinstall them. Moving to a different PCI slot does not fix it sadly. It has been happening more and more lately. Is it on its death bed? I am running the latest drivers and beta drivers. If so, what would you recommend to replace it with? The integrated sound does not work on my motherboard, just found that out as I was just going to use it (kinda sad it does not work on this high end motherboard). I have a Z-5500 sound system so I need a sound card that supports the 3 audio jacks and not optical as that is being used for my Apple TV. It can be PCI or PCI-E 1x as I have both slots open. If you need anything else, just ask.