Yeah.. i also forgot 1 important thing.. the PSU. the 8800GT's would be a PCI-E 6 pin each I'd get a Corsair TX750.. features 4 pci-express 6 or 8 pins connectors And should supply the cards with plenty of juice. cost about anoter $100 on top of the previous estimate. And aircool.. yes indeed.. the cheaper the cpu the better..and not really any need to overclock it.. the troughput between cpu and gpu.. or cpu and memory for that matter means nothing for GPU folding. read that the CPU/GPU doesn't even communicate more than every 20-30 seconds realtime.. its all about the GPU internally for folding.. amount of Stream processors and the shaderclock.. the amount of memory of the gpu and the memory clock has no visible impact on PPD. Also the X3210 is 1365 DKK here..and the q6600 1188 DKK.. so cheap here. Another alternative would be to run with something as low as a Celeron E1200 .. its a 1.6GHz dualcore with 0.5MB L2 Cache.. its a terrible performer.. but if your running windows vista on the folding machine this will be plenty of cpu power. (or possibly windows xp when that lame cpu usage bug is gone) that one comes at just 266 DKK.. (and for comparision $1 = 4.7 DKK) This would sure slow down windows vista etc.. but if its a dedicated folding machine it wont really matter. i'd wager its even good enough for a seperate machine for browsing the web while your gaming on your main rig etc. just don't do any CPU folding on it.. stick with GPU Rather spend the extra buck on a nice case and a few 120mm fans for intake and exhaust .. the 8800gt's can run a bit hot + would allow for a bit of extra shaderclock on the cards for better performance..