At least not in every game. I've been using it for a while now to take screenshots in certain games, and it suddenly stopped working. However, I just booted up another game and it seems to be working fine. I didn't touch any of the settings either. I updated to the absolute latest version as of today (version 4.6.1), and it's still not functioning. Just to clarify, the update didn't break it; I just updated it because I figured it'd fix it. The actual key that I use for screenshotting is working just fine. Tried changing hotkeys too, and still nothing. Everything else related to MSi Afterburner seems to be working normally. Any ideas?