If you cannot notice the difference then I would go with the best performance options. Anti Aliasing is a black art, there's many different methods and yet so few work these days and/or they work inconsistently from title to title. Easiest way to remember it is : Post Process AA - Often known as FXAA/Morphological or some in-house AA specific to the program. This is applied after the scene is rendered therefore reducing performance cost. However most of them apply a slight blur to the overall image. One additional benefit is that these post process AA can also help with transparency coverage. MSAA/FSAA - Classic and traditional full screen anti-aliasing. It costs more performance and only does standard shapes/objects - no transparency. Super Sampling/Transparency AA - Comes in simple names and more complicated Nvidia/ATI designations. Gives best image quality for transparency aliasing coverage. It's also the most performance heavy. Most people will be happy with post process AA. Particularly when you use a sharpening tool such as Sweet FX to bring detail back to areas that the AA blurred.