My vehicle is a quad-cab 2000 Dodge Dakota 4.7L V8, 4x4. It has nearly 220k miles on it. On occasion when starting the engine when the engine is already warm cylinder 2 will misfire for a while, a check engine light comes up with an OBD code of P0202 (cylinder 2 injector circuit malfunction), and eventually goes away after driving down the road a bit. It doesn't do it every time, either. I took a resistance reading with a multimeter of that fuel injector and got 15.7Ω. But, the service manual for my truck says the resistance of the fuel injectors should be 12Ω with a tolerance of 1.2Ω (10%). I also checked the resistance of a few other fuel injectors. Cylinder 8 injector is at 17.5Ω, cylinder 6 injector is at 14Ω, and cylinder 1 injector is at 19.2Ω. Last year I got a couple OBD codes randomly for the injector circuit malfunction on cylinder 1 and 8. I'm thinking that most, if not all of these injectors are out of spec and should probably be replaced soon. The other cylinders are harder to check the resistances on since they're a bit buried under stuff. Here is my question. Would it be wise for me to replace all the injectors at one time? They look pretty old and are most likely stock. It wouldn't surprise me if they have some deposit buildup as well which may contribute to the resistance problem. While the misfires are rare, I can eventually reproduce it with frequent stopping and starting of the engine while it is warm. I'm thinking if I replace them all now, even though it's more expensive in the short term, it's less work in the future.