Such protective mechanism is already implemented inside. Try to create RTSSHooks.dll.copy inside RTSS folder (such pending rename source file is placed there by installer) then attempt to start RTSS. It won’t allow you to start application prompting that reboot is required to finalize unfinished installation. But due to some odd reason I applied it to 32-bit hooks library only. I’ll do similar protection for 64-bit hooks too in the next version.