I just loaded the game. I'm just out of the Vault in the beginning, on the hill. With everything on max and Shadow Quality and Shadow Distance on High and God Rays on Low, I get a stuck 50fps (I have set the game at 1080p50Hz, after the horror stories I read in here). It hasn't dropped a frame yet. I've disabled its own Vsync and I'm using RadeonPro, along with Triple Buffering and the "Sync frame limiter to monitor refresh".