That option was not a troublemaker, please carefully read context help for it then the release notes explaining why exactly it is grayed out now. There is explicit warning in this option description, telling you that it is bad idea to enable it globally and recommending you to enable it at profile level only and only for applications actually using modified runtimes. There is explicit warning telling you that if you enable it for all applications it may prevent some of them from starting. Many users ignored it and simply keep it enabled then blame RTSS for being troublemaker. It is protected from being enabled blindly now.