So, a couple days later, right after I'm starting to relax, to think it's finally fixed... my fethin' computer goes blackscreen mid-game again. To recap: - Upgraded from 650Ti Boost to R9 380 - Used DDU from safe mode to remove the nvidia drivers (used clean and shutdown) - Installed R9 380. Computer blackscreening during gameplay galore. - Tried myriad of fixes, until finally trying card on different comp (which also previously had a nvidia card in it), got same issue on different comp - Got a replacement R9 380, issue persists - Got pointed to a drivers issue on Tom's Hardware, then posted here as well. - Re-ran DDU, cleaned both Nvidia and AMD driver, reinstalled AMD driver. Issue gone... for a couple days. Honestly I no longer know what to do. At this point I'll take pretty much any solution that isn't a clean reinstall of Windows (because doing that for easily the 20th time on this same computer is the last thing I wanna do). @ Wagnard: I'll send you the logs, then.