This is weird. I'm pretty sure this started happening with the last few builds of ATI Tray tools, since it has happened twice already. The first time, I reformatted windows 7 then installed the beta sp1. Not using skype or itunes at all, I installed ati tray tools. Restarted, and for some reason (did not know it was related to ati tray tools) both skype AND itunes (Actually, the newest versions of skype and itunes; skype 5, itunes 10.1) could not run. I tested skype 4 after (and before i reformatted) and profoundly it worked. I thought it was sp1 (even though 'minimal' changes were made), so i uninstalled sp1, and still, the problem kept occurring. So, i decided to reformat again (this time a slipstreamed version of sp1). Fast forward to today, when i realized i did not install ati tray tools (this was because i have had no time to play any games until now ). Installing ati tray tools, Skype DID NOT crash (it was in background). I start fiddling with the overclock, which crashes the driver (since i'm not careful enough). First time (display driver crashed): Skype did not crash, nor did i see any errors (other than the display driver crashing). (after messing up again) Second time: Skype crashed. I thought that was really weird, since if it would crash, it wouldn't be the second attempt at failing, it'll be the first. I restarted the computer and right when i get on the desktop, windows gives an application error about Skype and asks to send error info to microsoft. I realized this might be the exact same thing that happened to me before. Seeing if this was, in fact, the exact same problem, i opened itunes, and amazingly this also crashed. (This is around the time i realized att must be the problem). I closed att, and miraculously, both skype AND itunes suddenly started working. WHY does ATT crash (seemly unrelated) applications (btw i googled it and this seems to be isolated)? The answer is probably related to some setting (that i will need to turn off), and if so: How come this only started occurring in the last few builds? How come older versions of applications work while new ones don't (since skype 4 worked and skype 5 did not)? The graphics card probably is irrevelant, but the card is Mobility Radeon X1300 (yes a really old card; still plays the games i want though ) THANKS FOR HELPING Edit: Actually these two threads collaborate with this (incidently the top ones... which goes to show that this is a new problem) http://forums.guru3d.com/showthread.php?t=331037 http://forums.guru3d.com/showthread.php?t=332021 Now that i remember, does directx runtime have anything to do with this? I remember that steam games did not run becuase of some problem, and that you needed to install the runtime in order to play. Hmmm it doesn't make sense since skype or itunes do not require any directx (if it was, say, counter strike, then it would make sense).