The Nitro is using a custom PCB though far as overclock results go that's still up to chance though voltage might be better and the Nitro can go above 1.3v without crashing (Only Fury GPU that can?) though that's pretty high so unless you're trying to go above 1100Mhz (Or higher.) it's probably not worth going too crazy with upping voltage. Far as ASIC is concerned Fury GPU's tended to be around the 60's percentage going by GPU-Z (My own is at 52%) since it's the Fury X that gets the best binned chips (And the Nano I think is also getting pretty high quality ones.) though ASIC doesn't really relate to overclock results by any direct comparison either from what I've read up on. (Leakage might actually benefit overclocking a little bit even.) Oh and there's two Nitro models, one uses 1020Mhz and the other 1050 though the 1020 can probably be upped to 1050 without issue although some have problems going much higher than that but it's pretty random from what I've read with some GPU's not being able to go above 1070 without a heavy voltage increase whereas others can do 1100 and above so seems down to pure chance really what your own GPU will be able to achieve and what it will take to achieve such speeds while remaining completely stable. Another downside with the Nitro at least for more recent models is that it's not possible to unlock the disabled cores though performance is usually not affected by that much either from doing this although it can help occasionally even outside of benchmarking but as I far as I remember the stock Fury compared to Fury X was about 10% slower or some such really low number and that's in benchmarking software so they're pretty close already by default. VRM's get pretty hot too which some of the third party Fury GPU designs improve on over the stock water cooler although well the Tri-X and Nitro might have gotten points for it's silent and efficient cooler but that's primarily because it tends to stick around 20 maybe 30% speed by default, once it goes above 40% speed it gets pretty audible and above 60% it gets downright loud. It's still pretty effective even at lower speeds though aside from the occasional game that for whatever reason causes the GPU and VRM components to heat up to where the fan kicks in at 100% ha now that's a pretty high noise level.