I'm getting exactly the same problem and it seems for me a conflict with my samsung 970 500GB Evo M2 SSD as everything runs fine on my main drive...
Zotac GeForce GTX 1080Ti AMP Extreme Core Spectre RGB 11264MB Warrenty 5 years :)
If it wasn't for the modding community the game would be dead already!
I only buy Zotac now, as they give 5 year warranty :)
The 3 C's Computer Caffine Cigarettes
Recently my BFG 8800GTX Ultra died on me (After 2.5 years) and with the exellent warrenty from BFG they changed it for a new GTX 275 896 OCE...
I used to work for Watford electronics before it went bust and most of the cards that were brought back was XFX! I only buy BFG my 8800GTX Ultra...
Guru3d seems to be a little bit biased try reading this report! http://www.techspot.com/review/263-nvidia-geforce-gtx-480/
Try EVGA Precision Tool v1.3.3 This works great for me as I gave my kids my old 7900 and they had the same problem! Hope this helps.....