EK is releasing an Intel LGA1151 socket based monoblock belonging to the Quantum Line. The EK-Momentum Strix Z390-I is tailor-made for the ROG Strix Z390-I motherboard. The mini-ITX form factor often ... EK-Momentum ROG Strix Z390-I Monoblock for the mini-ITX ROG Motherboard
There's 7 ports on the back and another 5 (maybe 6? not totally clear) internal connectors, one of which is a type C port. How many more could you possibly need on an ITX build? Besides, as long as each host controller is directly accessible to the user, the number of USB ports is somewhat irrelevant. Boards that come with more ports are either using integrated hubs or are otherwise taking up PCIe lanes. Sure, using an external hub isn't exactly preferable, but it's not like you're getting 100% of the bandwidth out of every single port a computer offers you anyway.
Again, why not just use a hub? Those 12 ports you had were all connected through internal hubs. I bet you only had 3 total host controllers for those rear ports, maybe 4 if some were split for front ports. I've seen computers with 12 ports that actually only had 2 host controllers.