Upcoming Titles with GameWorks Technologies Assassin’s Creed: Unity= HBAO+, TXAA, PCSS, Tessellation. Batman: Arkham Knight= Turbulence, Environmental PhysX, Volumetric Lights, FaceWorks, Rain Effects. Borderlands:The Pre-Seque = PhysX Particles Far Cry 4 = HBAO+, PCSS, TXAA, God Rays, Fur, Enhanced 4K Support. Project CARS = DX11, Turbulence, PhysX Particles, Enhanced 4K Support. Strif = PhysX Particles, HairWorks The Crew = HBAO+, TXAA The Witcher 3 Wild Hunt = HairWorks, HBAO+, PhysX, Destruction, Clothing Warface = PhysX Particles Turbulence, Enhanced 4K Support War Thunder = WaveWorks, Destruction Source http://www.anandtech.com/show/8546/nvidia-gameworks-more-effects-with-less-effort But news for AMD user........
Most of those will work without problems on AMD cards. Except TXAA or GPU physx. The other stuff is mostly on CPU or DirectCompute.
Yeah it should work but performance might be a bit iffy or how to say depending on how it's implemented, could also have the effects rendering at a lower resolution / detail mode when a non-CUDA device is detected such as Call of Duty: Ghosts did it with the dog/wolf fur effect. As of the newer PhysX 3 runtimes CPU performance isn't that bad either as can be tested with the Metro Redux Games (Though those use the latest version of the PhysX SDK.) however the effects don't persist for very long before fading out. And as above TXAA requires CUDA so it won't work and it's up to the developers if the effects will be enabled on other GPU models. (The smoke effect in Assassin's Creed IV for example can't be enabled on non-Nvidia GPU's.)