I am 100% sure that this card will work with softquadro , but you will have to use the new detonator 4 drivers as they are the only ones that support the TI200. if you want to know how to patch drivers, check this link out. I went into detailed installtion directions.<br> <br> <A HREF="http://www.guru3d.com/forum/read_msg.php?tid=210&forumid=ubb11" TARGET=_blank>http://www.guru3d.com/forum/read_msg.php?tid=210&forumid=ubb11</A>