If you mean by "fully support" run a dx12 game, then yes. If you mean use all of DX12's features then no. http://www.extremetech.com/extreme/...what-amd-intel-and-nvidia-do-and-dont-deliver
No card today fully support all DX12's features. I would not worry about it though, R9 390 will do fine. If you checked latest Hitman dx12 benches 390 is performing even better than gtx980.